Clinical Trial

Effect of Cross-Education in Blood Flow Restriction Resistance Training on Lower Limbs in Older Women

Enrolling by Invitation
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Record status
This record was last updated February 11, 2026 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
Unilateral resistance training has been shown to promote strength adaptations in the directly trained limb and also improve strength in the contralateral limb, a phenomenon known as cross-education (CE), with more pronounced effects observed in high-load training. However, high-load resistance training may be unfeasible for older adults. Blood flow restriction (BFR) training emerges as a low-load alternative that reduces joint stress, is easy to apply, and has low cost. Although there is already evidence showing significant effects of CE during resistance training with BFR, gaps remain regarding its applicability in older adults. This study aims to evaluate the effects of CE in resistance training with BFR on the lower limbs of older women.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-08-27; most recent amendment 2026-02-10.
Trial Details
NCT Number NCT07155967
Lead Sponsor Paulista University
Conditions Muscle Strength, Hypertrophy
Enrollment 32 participants
Start Date 2025-08-11
Primary Completion 2026-07 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-02-11