A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient cohorts through serial blood draws and the acquisition of leftover tissue and/or bone marrow aspirates during their routine therapy and disease monitoring. The primary goal is to understand the association between biomarkers and real-world clinical outcomes in these patient populations.

NCT Number	NCT07154823
Lead Sponsor	Tempus AI
Conditions	Acute Myeloid Leukaemia (AML), Follicular Lymphoma ( FL)
Enrollment	550 participants
Start Date	2026-01-27
Primary Completion	2034-11 (estimated)
Study Completion	2035-11 (estimated)
Updated on ClinicalTrials.gov	2026-07-21