Small Bites Vs Large Bites Abdominal Midline Incisional Closure

The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique. The main questions it aims to answer are: Does small bite closure reduce the incidence of superficial surgical site infections (SSI), wound dehiscence, and incisional hernia compared to large bite closure? What are the associated complications of each closure technique? Participants will: Undergo either a small bite or large bite abdominal incision closure during emergency laparotomy Visit the clinic for follow-up assessments at 7 days, 15 days, 1 month, 3 months, and 6 months post-operatively Have their wound healing and complications documented and analyzed during respective visits.

NCT Number	NCT07154277
Lead Sponsor	Dow University of Health Sciences
Conditions	Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence, Incisional Hernia/Prevention and Control, Surgical Wound Infection
Enrollment	200 participants
Start Date	2023-11-23
Primary Completion	2025-12-24 (estimated)
Study Completion	2025-12-24 (estimated)
Updated on ClinicalTrials.gov	2025-09-04