Clinical Trial

The Resistant Starch Intervention for Cognitive Enhancement

Not Yet Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated September 3, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The investigation will explore the potential effects of resistant starch The Resistant Starch Intervention for Cognitive Enhancement study aimed to evaluate the effect of high-resistant starch diet intervention in slowing cognitive decline among individuals at high genetic risk for cognitive impairment. Participants will be randomly assigned to either an intervention group receiving daily high-resistant starch food products or a control group receiving isoenergetic regular starch products. The investigation will validate the potential effects of resistant starch on cognitive function protection and explore the underlying mechanisms through comprehensive data collection, including standardized neuropsychological assessments, laboratory biomarkers derived from blood and fecal specimens, and multimodal magnetic resonance imaging.
Protocol Amendment History 1 change
notable Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University -> Second Affiliated Hospital, Zhejiang University, School of Medicine 2026-08-09
Trial Details
NCT Number NCT07152483
Lead Sponsor Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions Cognitive Impairment, Diet Interventions, Cognitive Decline, Genetic Risk Factors, Obesity & Overweight
Enrollment 70 participants
Start Date 2025-09-01
Primary Completion 2026-04-01 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2025-09-03