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Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 6 months later Jun 1, 2026 → Dec 1, 2026
See other at-risk trials from Saglik Bilimleri Universitesi

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from Jun 1, 2026 to Dec 1, 2026
    • Study completion pushed from Jul 1, 2026 to Dec 30, 2026
    v3
  2. Secondary endpoints: details revised at 1 of 5 entries
    • Study description expanded, about 1 word
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread. Hard tissue grafts can produce "sticky bone," and bone gain can have a positive effect on intrabony defects frequently seen in periodontal disease, compared to grafts alone. This study aims to clinically and radiographically evaluate the effectiveness of using bovine-derived xenogenic bone grafts in combination with i-PRF and bovine-derived xenogeneic bone grafts alone in patients with intrabony defects and stage III periodontitis.
Trial Details
NCT Number NCT07146776
Lead Sponsor Saglik Bilimleri Universitesi
Conditions
(from sponsor)		 Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect, Periodontal Bone Loss
Related terms Alveolar Bone Loss, Periodontal Diseases, Periodontitis
Enrollment 16 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov