Clinical Trial

Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts

Recruiting
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Record status
This record was last updated September 8, 2025 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread. Hard tissue grafts can produce "sticky bone," and bone gain can have a positive effect on intrabony defects frequently seen in periodontal disease, compared to grafts alone. This study aims to clinically and radiographically evaluate the effectiveness of using bovine-derived xenogenic bone grafts in combination with i-PRF and bovine-derived xenogeneic bone grafts alone in patients with intrabony defects and stage III periodontitis.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-08-21.
Trial Details
NCT Number NCT07146776
Lead Sponsor Saglik Bilimleri Universitesi
Conditions Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect, Periodontal Bone Loss
Enrollment 16 participants
Start Date 2025-07-12
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-07-01 (estimated)
Updated on ClinicalTrials.gov 2025-09-08