Clinical Trial

Anastomotic Leakage After Colorectal Surgery.

Study acronym: AL
Recruiting
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Summary
Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL, determine its incidence and impact on outcomes, and develop a predictive model. Approximately 430 patients undergoing colorectal resection with anastomosis will be enrolled from August 2025 to August 2026. Risk factors will be assessed preoperatively, intraoperatively, and postoperatively. AL will be defined and graded per the International Study Group of Rectal Cancer (ISGRC) criteria.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-08-20; most recent amendment 2026-05-17.
Status change: Not Yet Recruiting → Recruiting 2025-08-27
Trial Details
NCT Number NCT07144683
Lead Sponsor Minia University
Conditions Anastomotic Leak, Colorectal Cancer, Diverticulitis
Enrollment 430 participants
Start Date 2025-08-25
Primary Completion 2026-08-25 (estimated)
Study Completion 2026-09-25 (estimated)
Updated on ClinicalTrials.gov 2026-05-19