Clinical Trial

The Effects of Prayer on Pain Thresholds and Scores of Anxiety and Depression in Patients With Migraine and Control

Completed
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Summary
The objective of this randomized single-blind crossover study is to evaluate the effect of prayer compared to the practice of reading a text (control) on the pressure pain threshold in individuals with and without migraine. The main topics it aims to answer are: * To analyze the relationship between individuals' spirituality, pain thresholds, and anxiety and depression scores. * To evaluate the effects of different aspects of prayer (thanksgiving, adoration, confession, meditative, and petitionary) on cephalic pain thresholds in individuals with and without migraines. Migraine group: 50 participants. Non-migraine group: 50 participants. Total number of participants in total: 100.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-08-19; most recent amendment 2026-02-23.
Status change: Recruiting → Completed 2026-01-09
Trial Details
NCT Number NCT07143461
Lead Sponsor University of Sao Paulo
Conditions Migraine
Enrollment 105 participants
Start Date 2023-09-29
Primary Completion 2025-09-29 (estimated)
Study Completion 2025-09-29 (estimated)
Updated on ClinicalTrials.gov 2026-02-25