BioHPP and Lithium Disilicate Onlay Restorations: Clinical Evaluation

In this study, clinical data obtained from the in vivo evaluation of onlay restorations fabricated with CAD/CAM using modified PEEK (BioHPP Shade 2, Bredent group GmbH \& Co. KG, Senden, Germany) and lithium disilicate (IPS e.max CAD, Ivoclar Vivadent, Schaan, Liechtenstein) ceramic materials will be analyzed, and the clinical outcomes will be assessed to investigate the clinical applicability of BioHPP. The clinical success of the restorations will be evaluated using established clinical evaluation criteria, specifically the modified United States Public Health Service (USPHS) criteria, focusing on parameters such as marginal adaptation, surface roughness, color match, anatomical form, and participant-reported outcomes. These restorations will be applied to molar teeth in the maxilla and mandible, provided that the teeth are vital and have no adjacent or opposing restorations. Only teeth meeting these inclusion criteria will be considered in the study.

NCT Number	NCT07142031
Lead Sponsor	Ege University Collaborators: The Scientific and Technological Research Council of Turkey
Conditions	Dental Caries, Polymers
Enrollment	40 participants
Start Date	2025-09-15
Primary Completion	2026-09-15 (estimated)
Study Completion	2026-10-15 (estimated)
Updated on ClinicalTrials.gov	2025-11-14