Pilot Study of a New Nerve Grafting Method During Bladder Cancer Surgery to Help Preserve Erections.

This pilot study will evaluate the safety and 1-year erectile function recovery in 10 patients undergoing a novel Nerve Restoring Radical Cystectomy (NR-RC), which includes a genitofemoral nerve graft. Erectile function will be assessed using IIEF-5, SF-MPQ, and CEEF questionnaires at baseline and at multiple post-operative intervals (4 weeks, 3, 6, 12, and 18 months). Safety will be monitored through peri- and post-operative complications, and additional demographic and clinical data will be collected for analysis.

NCT Number	NCT07140588
Lead Sponsor	Sir Mortimer B. Davis - Jewish General Hospital
Conditions	Bladder Cancer Requiring Cystectomy, Erectile Dysfunction Following Radical Prostatectomy
Enrollment	10 participants
Start Date	2025-09
Primary Completion	2028-09 (estimated)
Study Completion	2029-02 (estimated)
Updated on ClinicalTrials.gov	2025-08-24