"Transarterial Microembolization (TAME) in Inflammatory Knee Pathology"

Patients with knee OA and chronic pain refractory to at least 3 months of conventional conservative therapy will be included in the study, which will evaluate the clinical results obtained after treatment with selective arterial embolization (selection and enrollment, treatment with selective arterial embolization, follow-up checks). Forty-three patients will be included in the study and will undergo the transarterial microembolization procedure after signing the informed consent form for participation in the study and the collection of anamnestic data. Subsequently, patients will be followed up with clinical evaluation at 1, 3, 6, 12, and 24 months of follow-up or until possible dropout for other treatment.

NCT Number	NCT07140367
Lead Sponsor	Istituto Ortopedico Rizzoli Collaborators: Ospedale San Giuseppe Moscati, Avellino, Azienda Ospedaliero-Universitaria, Catania, Azienda Ospedaliera di Perugia, San Salvatore Hospital, AST Pesaro-Urbino, A.O.U. Città della Salute e della Scienza - Molinette Hospital
Conditions	Inflammatory Articular Diseases, Knee Osteoarthristis
Enrollment	43 participants
Start Date	2025-09-01
Primary Completion	2029-09-01 (estimated)
Study Completion	2031-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-07