Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD

This prospective study evaluates whether preoperative endoscopic ultrasound elastography (EUS-E) can predict pancreatic texture during surgery and risk of postoperative pancreatic fistula (POPF) in 100 patients undergoing pancreaticoduodenectomy. EUS-E measures pancreatic stiffness preoperatively. Intraoperative texture ("soft" or "hard") is assessed by surgeons blinded to EUS-E results. POPF is graded using ISGPF criteria. Predictive accuracy of EUS-E will be analyzed statistically.

NCT Number	NCT07139236
Lead Sponsor	Minia University
Conditions	Pancreatic Neoplasms, Pancreatic Fistula
Enrollment	100 participants
Start Date	2025-09-01
Primary Completion	2026-09-01 (estimated)
Study Completion	2026-10-01 (estimated)
Updated on ClinicalTrials.gov	2025-09-03