Clinical Trial

Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated August 24, 2025 (before its estimated December 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.
Trial Details
NCT Number NCT07138872
Lead Sponsor Gaziosmanpasa Research and Education Hospital
Conditions Percutaneous Nephrolithotomy (PCNL), Surgical Positioning, Prone Position, Supine Position, Hemodynamic Stability, Nephrolithiasis
Enrollment 84 participants
Start Date 2025-06-01
Primary Completion 2025-12-30 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-08-24