Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis

This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET/CT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.

NCT Number	NCT07138729
Lead Sponsor	Luo Yaping Collaborators: Peking Union Medical College Hospital
Conditions	Rheumatoid Arthritis (RA)
Enrollment	20 participants
Start Date	2025-05-10
Primary Completion	2027-12-01 (estimated)
Study Completion	2028-04-28 (estimated)
Updated on ClinicalTrials.gov	2025-08-24