Promoting Mental Health Among At-risk Adolescents in Malaysia

The primary objective of this trial is to evaluate a school-based intervention designed to promote mental health among at-risk adolescents from low-income communities in Malaysia. The study will employ a two-arm, cluster randomised controlled trial design, comparing a school-based intervention to a control condition. Adolescents will be recruited from at least 20 secondary schools located in economically disadvantaged rural and urban areas of Malaysia. Assessments will take place at multiple time points: during screening, at baseline (pre-intervention), immediately after the intervention (8 weeks), and at two follow-up points-6 and 12 months post-intervention. The primary outcomes are a reduction in anxiety and depressive symptoms, along with improved mental wellbeing at the 12-month follow-up.

NCT Number	NCT07138664
Lead Sponsor	University of Roehampton Collaborators: Universiti Malaysia Sabah, University Malaysia Sarawak, Universidad Complutense de Madrid, Sunway University, Saglik Bilimleri Universitesi, University of Exeter, University of Malaya, National University of Malaysia
Conditions	Depression in Adolescence, Anxiety
Enrollment	428 participants
Start Date	2025-08
Primary Completion	2026-09 (estimated)
Study Completion	2026-09 (estimated)
Updated on ClinicalTrials.gov	2025-08-24