SMART Implementation-Effectiveness Trial 1

While single maintenance and reliever therapy (SMART) has been the preferred management strategy for Step 3 and 4 (moderate/severe) asthma management since the 2020 NIH asthma guideline updates, adoption of SMART has not been rigorously assessed. This study will test electronic medical record clinical decision support and education implementation strategies (CDS+) to increase adoption of SMART in pediatric primary care. This is the first of two related records.

NCT Number	NCT07137923
Lead Sponsor	Children's Hospital of Philadelphia Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions	Asthma in Children
Enrollment	18 participants
Start Date	2025-09-03
Primary Completion	2027-08-31 (estimated)
Study Completion	2028-02-29 (estimated)
Updated on ClinicalTrials.gov	2025-09-17