Clinical Trial

Identifying Fundamental Mechanisms of Skeletal Muscle Ageing in Older Men Undergoing Androgen Deprivation Therapy: a Feasibility Study

Study acronym: MASS-ADT
Not Yet Recruiting
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Record status
This record was last updated August 21, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
To find out whether it is possible to run a study looking at the underlying markers of ageing in muscle quality and quantity in men receiving Androgen Deprivation Therapy for prostate cancer treatment. To determine the feasibility of conducting an observational study examining the association of fundamental biological markers of ageing with changes in body composition and skeletal muscle morphology following ADT in older men undergoing prostate cancer treatment.
Trial Details
NCT Number NCT07134439
Lead Sponsor Guy's and St Thomas' NHS Foundation Trust
Collaborators: King's College London
Conditions Sarcopenia, Prostate Cancer, Muscle Atrophy, Androgen Deprivation Therapy
Enrollment 20 participants
Start Date 2025-09
Primary Completion 2026-06 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-08-21