Clinical Trial

Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model

Completed Phase 3
View on ClinicalTrials.gov →
Summary
Clinical study to evaluate the anti-cavity effectiveness of three dentrifices using an intra-oral enamel Demineralization and Remineralization In-Situ Model. This is a six-week duration, Phase III, single-center, triple-blind crossover study. Thirty-six healthy adults will be randomly allocated to three groups for the treatment phases, which are interspersed with washout periods.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-08-14; most recent amendment 2026-02-05.
Status change: Active, Not Recruiting → Completed 2026-02-05
Status change: Not Yet Recruiting → Active, Not Recruiting 2025-11-20
Trial Details
NCT Number NCT07134231
Lead Sponsor Colgate Palmolive
Collaborators: Federal University of Alagoas
Conditions Demineralization, Remineralization, Dental Cavity, Enamel Lesions
Enrollment 36 participants
Start Date 2025-10-09
Primary Completion 2025-12-11 (estimated)
Study Completion 2025-12-11 (estimated)
Updated on ClinicalTrials.gov 2026-02-06