Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults

This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in institutionalized older adults aged over 75. The FEXO program combines aerobic, strength, balance, and flexibility training in a recreational format. Participants will be randomized to an experimental group (receiving the 14-week FEXO program) or a wait-list control group (continuing daily routines). After the first intervention phase, the control group will also complete the program. Primary outcomes include improvements in intrinsic capacity domains (cognition, locomotion, vitality, sensory, and psychological), frailty phenotype (Fried criteria), and physical function.

NCT Number	NCT07133581
Lead Sponsor	Cardenal Herrera University
Conditions	Frailty Syndrome, Sarcopenia
Enrollment	80 participants
Start Date	2025-09-04
Primary Completion	2025-12-19 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-21