Clinical Trial

Multimodal Imaging Evaluation of Vulnerability of Atherosclerotic Plaques: A Comparison of HR-VWI, OCT, and RWS

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Summary
The primary objective of this study is to evaluate the vulnerability of intracranial and extracranial atherosclerotic plaques using HR-VWI, OCT, and RWS technologies, while exploring correlations among these three imaging techniques. Secondary objectives include: 1) Investigating the relationship between RWS and plaque progression and identifying optimal RWS predictors; 2) Further evaluating the clinical value of RWS and HR-VWI in stroke prediction through two-year clinical and HR-VWI follow-up evaluations.
Trial Details
NCT Number NCT07133451
Lead Sponsor Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Conditions Intracranial Atherosclerotic Stenosis
Enrollment 561 participants
Start Date 2025-08-10
Primary Completion 2028-12-31 (estimated)
Study Completion 2030-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-08-21