Clinical Trial

Efficacy of Vonoprazan-based Rescue Therapy for H. Pylori Eradication

Name: Efficacy of Vonoprazan-based Rescue Therapy for H. Pylori Eradication — clinical trial record (NCT07130253)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Not Yet Recruiting

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Summary

1. This study aims to compare the efficacy of empirical vonoprazan-based therapy versus susceptibility-guided vonoprazan-based therapy for third-line eradication of H. pylori. 2. We also plan to explore the impact of eradication therapy on gut microbiota, fecal antibiotic resistance, and metabolic parameters before and after treatment.

Trial Details

NCT Number	NCT07130253
Lead Sponsor	National Taiwan University Hospital
Conditions	HELICOBACTER PYLORI INFECTIONS
Enrollment	220 participants
Start Date	2025-08-18
Primary Completion	2028-06-30 (estimated)
Study Completion	2030-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-08-19