Effects of a Peer-facilitated, Acceptance-based Self-learning for Illness Management (PASIM) Program

Psychosis is a very disabling mental illness with a wide range of dysregulations and disruptions in cognition, emotions, and behaviors, resulting in poor functioning and frequent relapses, especially in the first five years of the illness. There is a knowledge gap about whether Peer-facilitated, Acceptance-based Self-learning for Illness Management (PASIM) can have longer-term and more significant benefits than current professional-led psychoeducation in diverse health outcomes of these psychotic patients such as functioning, problem-solving, and recovery. This multi-center randomized controlled trial with repeated measures, 3-arm design is proposed to test and compare the effects between two alternative interventions (PASIM and Psychoeducation Group program) and a usual-care-only group over an 18-month follow-up.

NCT Number	NCT07129369
Lead Sponsor	Chinese University of Hong Kong Collaborators: Integrated Community Centers for Mental Wellness, Hong Kong, Psychiatric outpatient clinics
Conditions	Psychotic Disorders, Recent-Onset Psychosis
Enrollment	186 participants
Start Date	2026-01-02
Primary Completion	2028-08-31 (estimated)
Study Completion	2028-10-31 (estimated)
Updated on ClinicalTrials.gov	2025-08-19