Remote Intervention to Prevent Overdose

This Type 1 hybrid effectiveness-implementation randomized controlled trial, A Remote Intervention to Prevent Overdose among People who Use Stimulants and/or Opioids, aims to address the United States opioid crisis driven by fentanyl and other synthetic opioids by reducing overdose rates. It is supported by and included in the HEAL Initiative. This study would be the first national, fully remote trial to assess the impact of remote education on overdose outcomes, using a novel 2x2 design crossing remote education with remote access support. This research will inform scalability around remote education programs to address the nation's opioid overdose crisis.

NCT Number	NCT07128485
Lead Sponsor	University of Alabama at Birmingham Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Accidental Overdose of Opiate
Enrollment	100 participants
Start Date	2027-01
Primary Completion	2027-11 (estimated)
Study Completion	2027-11 (estimated)
Updated on ClinicalTrials.gov	2026-08-12