Clinical Trial

A Phase 1, SAD and MAD to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral FB-101 in Healthy Adult Male Subjects

Not Yet Recruiting Phase 1
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Record status
This record was last updated August 17, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
This is a Phase 1, randomized, double-blind, placebo-controlled study consisting of SAD and MAD investigation at a single clinical trial center conducted in healthy adult male subjects assessing the safety, tolerability, PK, and PD of oral FB-101 administration. Up to 72 healthy adult male subjects will be enrolled. Additional subjects may be enrolled (8 subjects per cohort) if it is deemed appropriate following review (e.g., in the circumstances where a dose level is repeated, or an intermediate dose is conducted or to add another dose level(s) (higher than those planned)).
Trial Details
NCT Number NCT07126704
Lead Sponsor 1ST Biotherapeutics, Inc.
Conditions Healthy
Enrollment 72 participants
Start Date 2025-11
Primary Completion 2026-06 (estimated)
Study Completion 2027-06 (estimated)
Updated on ClinicalTrials.gov 2025-08-17