Quality of Life in Children After Multisystem Inflammatory Syndrome in Children

The aim of this observational study is to assess whether Multisystem Inflammatory Syndrome (MIS-C) in children affects their quality of life. The investigators will examine whether there is a correlation between paediatric mortality prediction scoring systems, specific clinical and laboratory indicators, and whether some of these can predict the level of quality of life in children 24 months after hospital discharge. The primary questions are: Do children who survived MIS-C have a poorer quality of life 24 months after the illness compared to their peers? Can investigators identify prognostic indicators to create preventative strategies for MIS-C? The investigator will compare the quality of life in participants who survived MIS-C with a control group. The quality of life will be measured using a validated questionnaire. In the first phase, data from medical records will be collected. In the second, prospective part of the study, participants, healthy peers, and their parents or guardians will be asked to complete a questionnaire about quality of life.

NCT Number	NCT07126028
Lead Sponsor	Kristina Lah Tomulić
Conditions	Multisystem Inflammatory Syndrome in Children (MIS-C)
Enrollment	85 participants
Start Date	2024-04-01
Primary Completion	2025-07-31 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-08-17