Clinical Trial

Characterization of Gut and Tongue Coating Microbiota in Patients With Diminished Ovarian Reserve

Study acronym: CGTCMPDOR
Recruiting
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Record status
This record was last updated August 26, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to investigate the distinct tongue manifestation characteristics in patients with diminished ovarian reserve (DOR) compared to healthy individuals, and to clarify the features of tongue coating microbiota, gut microbiota, and their interrelationships in DOR patients. The main question it aims to answer is: Whether there are significant differences in tongue manifestations, tongue coating microbiota, and gut microbiota characteristics between DOR patients and healthy populations; Whether associations exist between tongue coating microbiota and gut microbiota in DOR patients; Whether the pathogenesis of DOR may influence estrogen metabolism through alterations in oral and gut microbiota.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-08-08.
Trial Details
NCT Number NCT07124260
Lead Sponsor Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Conditions Diminished Ovarian Reserve
Enrollment 200 participants
Start Date 2025-01-28
Primary Completion 2025-12-01 (estimated)
Study Completion 2025-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-08-26