Clinical Trial

The Correlation Between Red Cell Transfusion and Complications of Prematurity

Not Yet Recruiting
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Summary
The aim of this clinical trial is to learn if there is a correlation between the erythrocyte transfusion in the early neonatal period in premature infants and early and late complications of prematurity. The main questions it aims to answer are: * Do premature infants who receive blood transfusions within their first month of life have a higher risk of early prematurity complications, such as retinopathy of prematurity, necrotising enterocolitis, bronchopulmonary dysplasia, and intraventricular haemorrhage? * Do premature infants who receive blood transfusions during their first month of life have worse neurological and neurodevelopmental outcomes than those who do not? The first part of the study is retrospective, using data collected from participants' histories. The second part is prospective, evaluating neurological and neurodevelopmental outcomes at the age of six years.
Trial Details
NCT Number NCT07123948
Lead Sponsor Clinical Hospital Center Rijeka
Conditions Retinopathy of Prematurity (ROP), Bronchopulmonary Dysplasia (BPD), Enterocolitis, Necrotizing, Intraventricular Hemorrhage Neonatal
Enrollment 128 participants
Start Date 2025-09-01
Primary Completion 2028-12-31 (estimated)
Study Completion 2029-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-08-14