Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults. This real-time functional magnetic resonance imaging (fMRI) neurofeedback intervention delivers feedback based on a functional connection between the prefrontal cortex and the hippocampus.

NCT Number	NCT07122739
Lead Sponsor	Trustees of Princeton University Collaborators: National Institute of Mental Health (NIMH)
Conditions	Healthy
Enrollment	40 participants
Start Date	2025-07-17
Primary Completion	2027-12 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2026-02-23