Clinical Trial

Definitive Radiation Therapy for Inoperable Breast Cancer

Study acronym: DEFINE
Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-08-07.
Status change: Not Yet Recruiting → Recruiting 2025-12-15
Trial Details
NCT Number NCT07122713
Lead Sponsor Alexander Stessin
Collaborators: Northwell Health
Conditions Breast Cancer, Breast Adenocarcinoma
Enrollment 30 participants
Start Date 2025-12-08
Primary Completion 2028-12-30 (estimated)
Study Completion 2033-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-12-17