Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07121920 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD

StatusNot Yet Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study First Submitted
This study aims to test the overall hypothesis that the membrane tissue binding capacity of cytokines in the biopsied tissue of patients with Inflammatory Bowel Disease (IBD) is predictive of/strongly correlated to clinical response/outcomes observed. The key questions under investigation are: Aim 1: To assess the fluorescent signal intensity at baseline (control antibody with control biopsy and control antibody with IBD biopsy). Aim 2: To characterize the cellular landscape by surveying surface markers using bar-coded antibodies and performing gene expression profiling on every cell within inflamed tissue of patients with IBD. Aim 3: Develop algorithm using artificial intelligence to predict responders versus non-responders and to further subclassify IBD patients using phenotype data.
Trial Details
NCT Number NCT07121920
Lead Sponsor Cook Children's Health Care System
Conditions
(from sponsor)		 IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease
Related terms Inflammatory Bowel Diseases
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov