Clinical Trial

Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial

Active, Not Recruiting
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Record status
This record was last updated August 13, 2025 (before its estimated August 20, 2025 completion). Its status may not reflect the trial's current state.
Summary
This randomized controlled trial compared misoprostol and isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies. Low-risk women at 41+6 weeks gestation with an unfavorable cervix were randomized to receive either misoprostol or IMN. The primary outcome was the achievement of cervical ripeness (Bishop Score ≥6) within 40 hours.
Trial Details
NCT Number NCT07121634
Lead Sponsor Raid M. Al-Ani
Conditions Cervical Ripening
Enrollment 80 participants
Start Date 2024-01-01
Primary Completion 2025-08-20 (estimated)
Study Completion 2026-08-31 (estimated)
Updated on ClinicalTrials.gov 2025-08-13