This cross-sectional observational study investigates the relationship between climate change anxiety and chronic rhinosinusitis (CRS) symptom severity and quality of life (QoL) in adults. As climate change continues to influence public health, individuals with chronic respiratory diseases may experience worsened symptoms due to heightened psychological stress and perceived environmental instability. The study utilizes standardized instruments including the SNOT-22 (Sino-Nasal Outcome Test), a QoL scale, and a climate change anxiety questionnaire to evaluate associations among these variables.