Clinical Trial

Probenecid Administration for Alcohol Craving and Consumption

Study acronym: PROB2
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
This study proposes a 16-week, between-subject, double-blind, randomized controlled trial (RCT) with probenecid (2g /day) compared to placebo in individuals with AUD to test if reduces craving and alcohol consumption.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-08-11; most recent amendment 2026-03-14.
Status change: Not Yet Recruiting → Recruiting 2026-03-14
Trial Details
NCT Number NCT07118618
Lead Sponsor Brown University
Conditions Alcohol Use Disorder (AUD), Alcohol Consumption, Craving
Enrollment 120 participants
Start Date 2026-03-14
Primary Completion 2030-12-31 (estimated)
Study Completion 2030-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-17