Clinical Trial

Bromelain for Post-surgery Facial Swelling

Recruiting
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Summary
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-08-04; most recent amendment 2026-06-03.
Status change: Not Yet Recruiting → Recruiting 2025-09-19
Trial Details
NCT Number NCT07115212
Lead Sponsor Mohamed Bazina
Conditions Malocclusion
Enrollment 200 participants
Start Date 2025-09-08
Primary Completion 2028-05 (estimated)
Study Completion 2028-05 (estimated)
Updated on ClinicalTrials.gov 2026-06-05