Improving Sarcopenia in Cancer Patients Undergoing Chemotherapy With High-Protein Nutritional Supplementation

This study aims to investigate whether a high-protein nutritional supplement (ETHANWELL BALANCED) can help improve muscle strength and reduce fatigue in cancer patients who are at risk of sarcopenia (age- or disease-related muscle loss) during chemotherapy. Sarcopenia is common in older adults and cancer patients and can lead to weakness, poor treatment tolerance, and reduced quality of life. Participants aged 40 and older, receiving chemotherapy, and showing early signs of sarcopenia will be randomly assigned to two groups. The experimental group will receive nutritional education and take a high-protein nutritional drink three times per day for 8 weeks. Both groups will continue their usual medical care and perform simple resistance exercises at home. Researchers will measure changes in grip strength, fatigue, quality of life, and nutritional status over a 12-week period. This study will help determine whether early nutrition intervention can improve treatment outcomes and quality of life for cancer patients with sarcopenia.

NCT Number	NCT07114588
Lead Sponsor	National Taiwan University Hospital Collaborators: Ethan Nutraceutical Co., Ltd.
Conditions	Early-stage Sarcopenia in Adult Cancer Patients Undergoing Chemotherapy
Enrollment	57 participants
Start Date	2025-01-23
Primary Completion	2026-01-22 (estimated)
Study Completion	2026-01-22 (estimated)
Updated on ClinicalTrials.gov	2025-11-20