Clinical Trial

Optimal Ventilation for Cardiac Arrest

Study acronym: OPTI-VENT
Recruiting
View on ClinicalTrials.gov →
Summary
Pediatric cardiac arrest is a life-threatening problem affecting \>15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors. The objective of this study is to evaluate the effectiveness of the OPTI-VENT bundle to improve survival to discharge with favorable neurological outcome (Pediatric Cerebral Performance Category Score 1-2 or no change from baseline) among children receiving at least 1 minute of CPR.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-08-06.
Status change: Not Yet Recruiting → Recruiting 2025-10-07
Trial Details
NCT Number NCT07114510
Lead Sponsor Children's Hospital of Philadelphia
Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), University of Utah, Villanova University
Conditions Cardiac Arrest (CA)
Enrollment 1,530 participants
Start Date 2025-10-01
Primary Completion 2030-03-31 (estimated)
Study Completion 2030-03-31 (estimated)
Updated on ClinicalTrials.gov 2025-10-08