Vibroacoustic Therapy With Oscillating Positive Expiratory Pressure in the Treatment of Nasal Congestion

This is a prospective study. It enrolls subjects with allergic rhinitis, with or without asthma, who have nasal congestion as the main symptom and meet the inclusion criteria, aiming to evaluate the efficacy and safety of acoustic vibration combined with an oscillating positive expiratory pressure device in the treatment of patients with nasal congestion. On the premise that subjects agree to use basic medications (antihistamines, mometasone furoate nasal spray, ICS-LABA), they are instructed to use the acoustic vibration therapy device and the oscillating positive expiratory pressure therapy device respectively, 3 times a day for 3 minutes each time. Indicators related to nasal congestion will be measured immediately after a single use, as well as at 2 weeks, 4 weeks, and 8 weeks of use, so as to monitor the improvement of nasal ventilation and accompanying symptoms in the subjects.

NCT Number	NCT07114107
Lead Sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University Collaborators: Huzhou Central Hospital, The Children's Hospital of Zhejiang University School of Medicine, First People's Hospital of Hangzhou
Conditions	Atopic Rhinitis, Atopic Asthma
Enrollment	200 participants
Start Date	2025-08
Primary Completion	2026-03 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2025-08-11