Clinical Trial

Pressure-Volume Loop Assessment in Valvular Heart Disease

Study acronym: VHD-PV-loop
Recruiting
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Summary
The VHD PV loop study intends to assess invasive right ventricular to pulmonary artery (RV-PA) coupling in patients with valvular heart disease (VHD). Invasive RV-PA coupling is measured by using conductance catheters, the gold standard assessment for ventricular physiology. Several non-invasive parameters have been reported as surrogates for this complex physiological entity, but none of them has been tested against the gold-standard in this population. Based on this, our main objective is to assess the correlation of imaging derived RV-PA coupling in comparison to the invasive measurement.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-08-01; most recent amendment 2025-09-09.
Status change: Not Yet Recruiting → Recruiting 2025-09-09
Trial Details
NCT Number NCT07112391
Lead Sponsor Nantes University Hospital
Collaborators: Fédération Française de Cardiologie
Conditions Heart Failure, Structural Heart Disease, Interventional Cardiology
Enrollment 70 participants
Start Date 2025-09-04
Primary Completion 2027-09-04 (estimated)
Study Completion 2027-09-04 (estimated)
Updated on ClinicalTrials.gov 2025-09-16