Clinical Trial

Intravenous Tirofiban After Delayed Thrombolysis in Stroke

Name: Intravenous Tirofiban After Delayed Thrombolysis in Stroke — clinical trial record (NCT07111806)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: PEARL-TIRO

Not Yet Recruiting Phase 3

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Summary

A multicenter, double-blind, double-dummy, randomized trial evaluating the efficacy and safety of intravenous tirofiban in acute ischemic stroke (AIS) patients without large/medium vessel occlusion, who presented 4.5-24 hours after onset and received intravenous thrombolysis (IVT).

Trial Details

NCT Number	NCT07111806
Lead Sponsor	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Conditions	Acute Ischemic Stroke
Enrollment	852 participants
Start Date	2025-12-01
Primary Completion	2028-12-01 (estimated)
Study Completion	2029-03-01 (estimated)
Updated on ClinicalTrials.gov	2025-08-08