Neuromodulation and Attention Deficits in MDD

Multimodal study (Behavior, TMS, EEG) combining a sham-controlled intermittent theta burst stimulation (iTBS) intervention with an additional-singleton task and EEG to evaluate whether left dorsolateral prefrontal cortex (DLPFC) stimulation enhances cognitive control and modulates maladaptive attention processes in MDD and whether the effects are influenced by neuronavigated versus manual (Beam F3 method) localization of the stimulation site.

NCT Number	NCT07111169
Lead Sponsor	University of Electronic Science and Technology of China
Conditions	Major Depression Disorder, Cognitive Deficits, Selective Attention
Enrollment	60 participants
Start Date	2024-01-01
Primary Completion	2028-12-30 (estimated)
Study Completion	2028-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-08-08