Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries. It also aims to evaluate the impact of both medications on intraoperative regional cerebral oxygen saturation (rSO₂).

NCT Number	NCT07108764
Lead Sponsor	Tanta University
Conditions	Intraoperative Infusion, Lidocaine, Dexmedetomidine, Cerebral Oxygen Saturation, Postoperative Delirium, Elderly Patients, Abdominal Surgeries
Enrollment	100 participants
Start Date	2025-04-17
Primary Completion	2027-04-01 (estimated)
Study Completion	2027-04-01 (estimated)
Updated on ClinicalTrials.gov	2025-08-07