Interactions Between Placebo Effects and Mindful Awareness State

In this experiment,the investigators study the effects of interpersonally induced placebo effects and a mindful awareness induction on negative affect. Specifically, it will be examining the effects of interpersonally induced placebo effects (sham tDCS vs. control) and a mindful awareness induction (mindful state vs. control), as well as their interaction. Each group will undergo fMRI scanning and physiological recording will performing the Multimodal Negative Affect Task (MNAT).

NCT Number	NCT07108101
Lead Sponsor	Trustees of Dartmouth College
Conditions	Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
Enrollment	120 participants
Start Date	2026-06-01
Primary Completion	2028-06-01 (estimated)
Study Completion	2028-11-30 (estimated)
Updated on ClinicalTrials.gov	2025-08-06