Genetic Study to Determine the Cause of Birth Defects in Newborns in Texas

The purpose of this study is to provide advanced genetic testing and virtual consultations for seriously ill newborns in hospitals in Texas with fewer resources, especially along the Texas-Mexico border. The researchers also want to know how well the virtual consultation tool, called Consultagene, works in these hospitals by gathering feedback from healthcare providers. Researchers will provide rapid whole genome sequencing (WGS) to 200 infants over a period of 5 years. Data will be collected via Consultagene, surveys, and qualitative interviews.

NCT Number	NCT07102966
Lead Sponsor	Baylor College of Medicine Collaborators: National Human Genome Research Institute (NHGRI)
Conditions	Rare Diseases
Enrollment	410 participants
Start Date	2025-10-28
Primary Completion	2029-03-31 (estimated)
Study Completion	2029-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-27