An Efficacy and Safety Study of LTG-001 Following Abdominoplasty

The goal of this clinical trial is to learn if LTG-001 works to treat post-operative / acute pain after an abdominoplasty procedure. It will also learn more information on the safety of LTG-001. The main questions it aims to answer are: Does drug LTG-001 treat the acute pain after surgical abdominoplasty over 48 hours? How tolerable is LTG-001 over 48 hours? What dose of LTG-001 is better for treating post-operative / acute pain? Participants will: Take LTG-001 bid after the surgical abdominoplasty. Remain at the clinic for approximately 48 hours during study dosing and return after two weeks for a safety check up. Report the pain relief during the 48 hours to record changes in the post-operative pain.

NCT Number	NCT07102459
Lead Sponsor	Latigo Biotherapeutics
Conditions	Acute Pain, Postoperative Pain Control
Enrollment	343 participants
Start Date	2025-07-24
Primary Completion	2026-01-07 (estimated)
Study Completion	2026-01-07 (estimated)
Updated on ClinicalTrials.gov	2026-04-29