Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain

This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the movement evoked pain in healthy and patients with chronic primary pain (e.g., fibromyalgia). The intervention lasts 3 weeks with two treatment sessions per week.

NCT Number	NCT07101978
Lead Sponsor	Bern University of Applied Sciences Collaborators: Dr. med. h.c Erwin Braun Stiftung
Conditions	Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease, Rheumatic Diseases, Musculoskeletal Diseases, Neuromuscular Disease, Fibromyalgia +5 more
Enrollment	60 participants
Start Date	2026-08-01
Primary Completion	2028-08-30 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-02