Vitamin B12, Folic Acid and Vitamin D Status in Women of Reproductive Age

This cross-sectional observational study aims to assess serum concentrations of vitamin B12, folic acid, and vitamin D in women of reproductive age in Herzegovina. The study is led by Professor Vajdana Tomić, MD, PhD, who serves as the Principal Investigator, at the Faculty of Health Studies, University of Mostar, Bosnia and Herzegovina. The goal is to determine whether current international supplementation guidelines reflect the actual micronutrient status of this population. A total of 360 women aged 18-49 will be enrolled between December 2024 and December 2025 after providing informed consent. The findings will inform population-specific recommendations for micronutrient supplementation during the preconception period and pregnancy. The study will be conducted at the Faculty of Health Studies, University of Mostar, Bosnia and Herzegovina.

NCT Number	NCT07100795
Lead Sponsor	University of Mostar Collaborators: Faculty of Health Studies - University of Mostar, Primary Health Care Center Mostar, University Clinical Hospital Mostar
Conditions	Vitamin D, Vitamin B 12 and Folic Acid Concentrations, Micronutrient Status in Women of Reproductive Age, Vitamin Status Assessment
Enrollment	360 participants
Start Date	2024-12-23
Primary Completion	2026-12-01 (estimated)
Study Completion	2026-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-06