Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy

The purpose of this study is to evaluate the effectiveness of a psychosocial intervention called iTEST for people with psychotic disorders that targets introspective accuracy, or the ability to accurately gauge ones abilities. iTEST combines daily cognitive training on a mobile device with coaching that addresses recovery goals. In this trial, we will randomize people to one of two interventions conditions, iTEST or a control condition that receives coaching and cognitive training that does not emphasize introspective accuracy. Both interventions will take place over 12 weeks and participants will be asked to complete assessments at baseline, 6 weeks, 12 weeks, and 24 weeks. The primary outcome of the study is community functioning. Participants will be from three metropolitan areas: San Diego, Dallas, or Miami.

NCT Number	NCT07098169
Lead Sponsor	University of California, San Diego Collaborators: National Institute of Mental Health (NIMH), The University of Texas at Dallas, University of Miami
Conditions	Schizophrenia Disorders, Schizoaffective Disorder, Psychotic Disorder
Enrollment	201 participants
Start Date	2025-09-01
Primary Completion	2028-02-01 (estimated)
Study Completion	2028-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-23