Clinical Trial

Analgesic Effect and Safety of Oliceridine and Oxycodone in Vitrectomy

Not Yet Recruiting
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Record status
This record was last updated July 31, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
Traditional opioid analgesia is a method to treat moderate to severe pain. However, the use of opioids is not without risks. When treating acute pain, patients may have hypotension, respiratory depression, hypoxia, nausea and vomiting, irritability and pruritus. The aim of this study was to evaluate the analgesic effect and safety of g-protein-biased μ - opioid receptor agonists Oliceridine and oxycodone in vitrectomy.
Trial Details
NCT Number NCT07097038
Lead Sponsor Henan Provincial People's Hospital
Conditions Vitrectomy
Enrollment 120 participants
Start Date 2025-07
Primary Completion 2025-12 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2025-07-31