Clinical Trial

Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease

Recruiting Phase 1
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Record status
This record was last updated July 30, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
To investigate the safety of deep brain stimulation (DBS) and cervical deep lymphoid-venous anastomosis (LVA) in the treatment of severe Alzheimer's disease (AD); to investigate the effectiveness of DBS and LVA in the treatment of severe AD, i.e., effects of deep brain stimulation on cognitive function, emotion and life quality in patients with severe AD.
Trial Details
NCT Number NCT07094438
Lead Sponsor Chinese PLA General Hospital
Conditions Alzheimer Disease
Enrollment 98 participants
Start Date 2025-01-01
Primary Completion 2026-06 (estimated)
Study Completion 2027-07 (estimated)
Updated on ClinicalTrials.gov 2025-07-30