Corticosteroid Versus PRP Injections for Shoulder Tendinopathy

Shoulder tendinopathy is a common condition that causes shoulder pain and limits daily activities. It often results from damage or overuse of the rotator cuff tendons. Treatment typically includes rest, physical therapy, anti-inflammatory medications, and sometimes injections. This clinical trial aims to compare the effectiveness of two types of injections for treating simple shoulder tendinopathy: Corticosteroid injections, which reduce inflammation and provide quick pain relief, but may have only short-term effects. Platelet-Rich Plasma (PRP) injections, a newer treatment made from the patient's own blood, which may promote long-term healing. The study is being conducted at the Rheumatology Department of Charles Nicolle Hospital in Tunis, Tunisia. A total of 60 adult patients with shoulder tendinopathy will be randomly assigned to receive either a corticosteroid injection or a PRP injection. Participants will be evaluated before the injection (baseline), after one week, and after three months. The researchers will assess pain levels using a visual analog scale (VAS), and shoulder function using validated questionnaires (DASH and SPADI scores). The goal is to determine which treatment provides better pain relief and functional improvement over time.

NCT Number	NCT07094178
Lead Sponsor	Hopital Charles Nicolle
Conditions	Tendinopathy of Rotator Cuff
Enrollment	60 participants
Start Date	2025-06-30
Primary Completion	2025-10-01 (estimated)
Study Completion	2025-11-01 (estimated)
Updated on ClinicalTrials.gov	2025-07-30