Biomarkers, Risk Assessment, Imaging, and Neurodegeneration in Cerebral Small Vessel Disease (BRAIN-CSVD)

The BRAIN-CSVD study is a single-center prospective cohort study focusing on cerebral small vessel disease (CSVD).Patients enrolled in this research will undergo assessments for vascular risk factors, cognitive and other neurological functions, neuroimaging, and biomarkers. The study aims to explore imaging and biomarker predictors of CSVD progression, and the pathophysiological mechanisms of CSVD.

NCT Number	NCT07093515
Lead Sponsor	Zhejiang Hospital
Conditions	Cerebral Small Vessel Disease
Enrollment	500 participants
Start Date	2025-10
Primary Completion	2030-12-30 (estimated)
Study Completion	2032-12-30 (estimated)
Updated on ClinicalTrials.gov	2025-07-30